Below are the main rubriks (i.e strongest indications or symptoms) of Apis Mel in traditional homeopathic usage, not approved by the FDA.
Apis Mellifica acts on cellular tissues causing oedema of skin and mucous membranes.
The very characteristic effects of the sting of the bee furnish unerring indications for its employment in disease. Swelling or puffing up of various parts, EDEMA, red rosy hue, stinging pains, soreness, intolerance of heat, and slightest touch, and afternoon worse are some of the general guiding symptoms. Erysipelatous inflammations, dropsical effusions and anasarca, acute, inflammation of kidneys, and other parenchymatous tissues are characteristic pathological states corresponding to Apis Mellifica. Apis acts especially on outer parts, skin, coatings of inner organs, serous membranes. It produces serous inflammation with effusion, membranes of brain, heart, pleuritic effusion, etc. Extreme sensitiveness to touch and general soreness is marked. Constricted sensations. Sensation of stiffness and as of something torn off in the interior of the body. Much prostration.