Digitalis Purpurea - Appendix symptoms - T.F. Allen

APPENDIX

Authorities

1, Baehr, Monograph Digitalis (pulse before experiment averaged, in bed, mornings 51, on rising 60, after breakfast 63, evening 65, evening after exercise 69, evening in bed 59), took 2d trit. 1/5 gr. at 10.30 A.M. first day, at 10.25 A.M. second and third days, at 9.30 A.M. fourth day; 1/2 gr. at 10.5 A.M. fifth day, at 9.40 A.M. sixth day; 1 gr. at 10.45 A.M. seventh day; 1b, same prover, second proving with 2d trit., 1 1/2 gr. at 10 A.M. first day, 11.45 A.M., second day, 2 grs. at 9.55 A.M. fourth day, 2 1/2 grs. at 10.45 A.M. seventh day, 2 grs. at 9.10 A.M. eighth day, 2 1/2 grs. at 10.28 A.M. ninth day, 2 grs. at 10.40 A.M. fifteenth day, 2 grs. at 10 A.M. sixteenth day, 2 grs. at 10 A.M. eighteenth day, 3 grs. at 9.59 A.M. nineteenth day, 3 grs. at 10.30 A.M. and 1 gr. at 10.30 P.M. twenty-first day, 3 grs. at 9.58 A.M. and 1 gr. at 11 P.M. twenty-third day, 3 grs. at 9.30 A.M. twenty-fifth day, 3 grs. at 10.40 A.M. twenty-sixth day; 2, Baehr's wife, aged 28, took 2d trit, one dose of 1 gr. (pulse 72 sitting, 92 standing); 2b, same prover took again 2d trit. 2 grs. first day, 1 gr. evening second day, 2 grs. morning third day, 3 grs. morning fourth day, 3 grs. morning sixth day; 3, Baehr's proving on a man with 2d trit., 1/2 gr. first day, 1 gr. third day, 1 1/2 gr. fifth day; 4, Lembke, provings 1/50 gr. (pure) doses (six provings) N. Z. f. H. Kl., 4, 177; 5, Homolle et Quevenne, Archiv f. Phys., Jan., 1854, first proving with doses of 4 mill. a day for 8 days, 6 mill. on ninth day; 6, same, second proving, doses of 4 mill. a day for 6 days; 7, same, doses of 2 of 6 mill. a day for 8 days; 8, Leroux, effects of overdose, 30 granules in two doses (30 milligrammes), on a patient aged 62, with oedema of legs (L'Union Méd., 1852), from Homolle et Quevenne; 9, effects of getting some into the eye, H. and Q., p. 202; 10, Treves, case of attempted suicide, from Husemann, Pflanzenstoffe; 11, poisoning of the window De Pauw, from Husemann; 12, poisoning of a woman, aged 34, by 46 granules (?), Union Med., 1854 (from Tardieu); 13, Heer, poisoning of a woman by 16 and 40 granules (?), Union Med., 1857; 14, Hardy, poisoning of a pregnant woman, Archiv Gén. de Méd., 1864; 15, Stadion, general results of experiments on self, Prag. Vjsch., 74, 97, from Hom. Obs., 1864; 16, Dubue, poisoning of a man, aged 45, by 45 to 50 granules, Gaz. d'Hôp., 1865; 17, Nunneley, general results of experiments, B. and F. Med.-Chir. Rev., 1869; 18, Magnin, poisoning of a woman with an affection of heart by 1/4 of a grain, Gaz. hebdom., 1874; 19, Homolle, London Chemist, 1845, from Journ. de Pharm., took five doses of 5 milligrammes each for three days, at intervals of four or five hours; 20, Winogradoff, effects on several persons of all ages while taking 3/10 to 2/7 of a grain in twenty-four hours for five days; Virchow, Archiv, from Syd. Soc. Year-book, 1862, p. 452; 21, T. L. Brunton, effects on self (conclusions only taken, tables and sphygmographic tracings omitted, the latter not at all characteristic), Monograph, London, 1868, p. 23, et seq.

EYE.

EAR.

SKIN.

SUPPLEMENT DIGITALIS.

SUPPLEMENT.

1, Hahnemann, Chr. Krn., 3, 230; 2, Becher, ibid.; 3, Franz, ibid.; 4, Gross, ibid.; 5, Hornburg, ibid.; 6, Jahr, ibid.; 7, Langhammer, ibid.; 8, J. Lehmann, ibid.; 9, Meyer, ibid.; 10, Piepers, ibid.; 11, Rückert, ibid.; 12, Stapf, ibid.; 13, Teuthorn, ibid.; 14, Trinks, ibid.; (15 to 51, authorities quoted by HAHNEMANN); 15, Baidon, Edinb. Med. and Surg. Journ., III, 271, "statement from observation;" 16, Baker, Med. Trans. of Lond. Collinsonia Canadensis ^Coll. of Phys., III, art. 17, "effects of Digitalis in a case of anasarca;" 17, Baylies, Pract. Essays on Medical Subjects ("not obtainable"); 18, Beddoes, Med. Facts and Obs., V, art. 2, "from an overdose;" 19, Boerhaave, Hist. Plant, 1731, p. 308, "observed effects;" 20, Drake, Med. and Phys. Journ., IV, 521, "effects of Digitalis when given for phthisis;" 21, Edinb. Med. Comm., X, 358, "from overdosing;" 22, Gremler, in Rust's Mag., XXV, 578, "from overdosing;" 23, Guibert, Gaz. de Santé, 1826, "effects of Digitalis in a case of enlarged heart;" 24, Haller, in Vicat's Mat. Med., I, 112, "statement from authors;" 25, Henry, Edinb. Med. and Surg. Journ., VII, 148, "from overdosing an ascitic patient;" 26, Horn, Neues Archiv, I, 504 ("nothing about Digitalis here"); 27, omitted (see Nos. 52 to 62); 28, Journal de Chimie, 1827, p. 593, "from an overdose;" 29, Kinglake, in Beddoes ("nothing from him found here"); 30, Kraus, in Hufeland's Journ., v. 3, 182, "as Baker;" 31, Kurtz, in Jahn's Med. Convallaria Majalis ^Conv. Bl., 1830 ("not obtainable"); 32, Lentin, Beobacht., 1774, p. 167, "from an overdose;" 33, Lettsom, Mem. of Med. Soc. of Lond., II, art. 16, "effects of Digitalis when given to dropsical patients;" 34, Maclean, Med. and Phys. Journ., II, 119, "effects on patients;" 35, Mangold, in Horn's Archiv, III, 1, 141 ("not obtainable"); 36, Mayer, Richter's Chir. Biblioth, V. 531, "effect of Digitalis given for mammary scirrhus;" 37, Monro, Samml. f. pr. Aezt., XIII, 288, "effect of Digitalis given for dropsy;" 38, Mossmann, I, Essay on Scrofula, "not obtainable;" 39, Mossmann, II, Med. and Phys. Journ., III, 13, "effects of Digitalis given in pneumonia;" 40, Müller, in Nasse's Zeitsch. f. Anthracinum ^Anthr., I ("not obtainable"); 41, Neumann, in Hufel. Journ., LV, 58, "effects of Digitalis in phthisis;" 42, Penkivil, Med. and Phys. Journ., III, 315, as Neumann; 43, Percival, Med. Facts and Exper., I, 113, "effects of Digitalis given in hydrocephalus;" 44, Quarin, Animadv. Pract., p. 118, "nothing about Digitalis here, but most of his symptoms cited in Baylis's Bibl. de Therap., III, 320, effects of Digitalis given for scrofula;" 45, Remer, Annal. d. Kl. Aust., I, "not obtainable;" 46, Sackreuter, Annal. d. Heilk., 1811, "not obtainable;" 47, Schiemann, Diss. de Dig. Purp., 1786, "not obtainable;" 48, Schriven, Med. and Phys. Journ., III, 207, "from overdose;" 49, Troschel, Hufeland's Journ., 1829, p. 127, "a translation of Guiberth's case;" 50, Warren, Lond. Med. Journ., VI, 2, 145, "from overdose;" 51, Withering, Account of the Foxglove, 1785, effects of Digitalis observed on patients; (52 to 62, Jörg's provings, Materialen Zur Heilmittellehre); 52, Güntz took 1/4 of a grain of the leaves with 2 grains of magnesia, afterward 1 gr. with magnesia, and afterward 2 grs. with magnesia; 53, Heisterbergk took 1/4 to 1 gr. with 4 grs. of magnesia; afterwards 2 grs without magnesia, afterwards 2 grs without magnesia, afterwards 2 1/2 grs. with magnesia; 54, Knesche took 1/4, 1/2, 3/4, 1, 1 1/2, and 2 grs., each with magnesia; 55, same prover took of an infusion of 1 scruple of leaves to 4 ounces of water, one spoonful, afterward 12 to 25 drops of the tincture (1 part leaves to 6 parts of spirits); 56, Seyffert took 1/4, 1/2, 1 1/2, and 2 grs. with magnesia; 57, same prover took infusion and tincture; 58, Otto took 1/2 gr. first day, 3/4 gr. second day, each with magnesia, 1 1/4 grs. third day, 1 1/2 grs. fourth day, 2 grs. fifth day, 2 grs. seventh day; 59, Siebenhaar took 1/2 to 1 1/4 grs. with magnesia; 60, same prover took 1/2 to 3 grs. without magnesia; 61, Jörg took 1/4 gr. with sugar first day, 1/2 gr. second day, 3/4 gr. with magnesia fourth day, 1 gr. in water fifth day; 62, Mad. Ch. took 1/4 gr. with sugar first day, 1/2 gr. second day, 1/2 gr. with magnesia fourth day; 63, Schrön took 1 gr. of powder in water first day, 2 grs. second day, after three days took 3 grs; 63b, same prover, after waiting a month, took 1/2 gr. three times a day for three days (from Baehr's monograph on Digitalis); 64, Baehr took tincture, 10 drops at 11 A.M.; 64b, same prover took, first day, 10 drops at noon, second day, 10 drops evening, fourth day, 15 drops at noon; 64c, first day, 15 drops noon, second day, 18 drops evening, third day, 20 drops evening; 64d, first day, 1/2 gr. of powder forenoon, second day, 1/2 gr., third day, 1 gr., fourth day, 1 gr., fifth day, 1 gr., sixth day, 1 1/2 grs.; 64e, first day, 1 1/2 grs. forenoon, 1 gr. evening, second day, 1 1/2 grs. forenoon; 64f, one dose of 1 1/2 grs.; 64g, first day, 32 drops tincture morning, 20 drops evening, second day, 20 drops morning, third day, 30 drops evening; 64h, one dose, 2 1/2 grs., in morning; 65, Dr. Hutchinson (Joumides, Progres d. Sc. Med., 1821, from Dr. Black's article in B. J. of Hom.), took repeated doses of 60 drops until 420 drops were taken in three days; 65b, same took 10 to 70-drop doses till 2220 drops were taken in sixteen days; 65c, same took 12 to 40-drop doses every eight hours till 1694 drops were taken in fourteen days; 66, Dr. Francis Black took tincture, first day, 10 drops, second day, 10 drops at 10 A.M. and 2 P.M., fourth day, 20 drops, fifth day, 25 drops, seventh day, 30 drops, fourteenth day, 25 drops at 11 A.M., and 15 at bedtime, sixteenth day, 36 drops at 11 A.M. and 20 drops in evening; 67, Dr. L. took 10 to 36 drops daily for six days, in all 172 drops (only one symptom, headache); 68, Dr. K. took tincture several days, 10 to 60-drop doses (only one symptom, urine); 69, a friend of Dr. Black took one dose of 20 drops of tincture; 70, Dr. Saunders took 15 drops night and morning for three days, 25 drops fourth day, 50 drops seventh day; 71, Purkinje, Beob. und Vers., 1825 (Frank's Mag., 4, 154), took 3 grs. of aqueous ext. daily for four days; 71b, same took an infusion of 2 drs. of leaves to a pint of water; 72, Hammond, proving on a man, aged 25, with tincture, 20 min. three times a day for three days, Am. J. M. Sc., 1859; 73, Gourvat, anaphrodisiac action (Gaz. de Paris), Phil. Med. Times, 3, 463; 74, Cattel, symptoms compiled, B. J. of Hom., 11, 170; 75, Homolle et Quevenne, Mémoire sur la Digitaline et la Digitale, 1854, proving with powdered Dig. (in pills), 0.20 to 0.30 grms. daily for eight days; 76, Oulmont, poisoning of a woman, aged 22, by a teaspoonful of the tincture taken for palpitations, Lond. Med. Gaz., 2, 989, 1851; 77, De Colleville, poisoning of a woman, aged 68, by an infusion of 15 grammes of dried leaves, taken for oedema of lungs when nearly convalescent (Journ. de Méd. de Bordeaux), Lond. Med. Gaz., 1849; 78, Cabaret, a man, aged 55, took half a glassful of the juice of Dig. for intermittent fever, B. J. of Hom., 1, 411, from Oppenheimer's Zeit., 1843; 79, Quebec Daily News and P. J., Feb. 1865, B. and F. Med.-Chir. Rev., 1865, poisoning of three men by the tincture; 80, Perrin, poisoning of a young man by decoction of the leaves, Gaz. des Hôp., 1874, p. 925; 81, Mozel, fatal poisoning of a woman, aged 22, by an infusion of 3 1/2 grammes of the leaves, Gaz. d. Hôp., 1864; 82, A. Taylor, fatal poisoning, by 6 ounces of a decoction of the leaves, from Tardieu Empoisonnement, p. 798; 83, same, fatal poisoning of a young man by a decoction; 84, Causse, poisoning of a pregnant woman by the juice, Ann. d'Hyg., 1859; 85, G. Wilson, poisoning of a young man by two teaspoonfuls of a very strong infusion for a sore throat, Lond. Med. Gaz., 1864; 86, Edward, poisoning by an infusion of 2 ounces of the root, Lancet, July, 1849; 87, Fogo, poisoning of an asthmatic patient by 1 ounce, N. Eng. Med. J., 12, 81 (from Ed. M. J., No, 72); 88, Brughmans, general effects of 0.30 to 0.40 centigr. of powder for five or six days, from Homolle and Quevenne, Mémoire sur la Dig.; 89, Vassal, effects on a woman, aged 44, of doses of 2 centigr., Diss. sur la Dig., p. 79, from Homolle and Quevenne; (90, 91, 92, omitted;) 93, Dr. Lewis Burwell, Inaug. Diss., Philadelphia, 1805, having fasted and taken moderate exercise till 10 A.M., took 1/4 gr. of powdered leaves, repeated after two hours and a half, and several times with similar results; 94, Dr. Barton (quoted by last authority), several persons took Dig. unintentionally; 95, Lembke, proving with 1/4 gr. of powdered leaves, first, sixth, and thirteenth days, 1/2 gr. twenty-second and twenty-eighth days, 3/4 gr. forty-seventh day, and 1 gr. seventy-ninth day, N. Z. f. Hom. Kl., 2, p. 171.

Supplement

DIGITALIS.

Authority.104, Drs. Flechner, Frankel, Schneller, and Winternitz, Zeit. der k. k. Gesel. dur AErzte zu Wien, 1847, p. 171, three men made a proving with the tincture, beginning with 2 drops and increasing to 160, and in one case to 400.