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Jaborandi (Pilocarpus) - General symptoms - T.F. Allen

Pilocarpus, Jaborandi, Pilocarpinum Hydrochloricum, Pilocarpinum Jab.


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HPUS indication of Jaborandi (Pilocarpus): Sweat profuse
Common symptoms: Sweat, profuse.

Below are the main rubriks (i.e strongest indications or symptoms) of Jaborandi (Pilocarpus) in traditional homeopathic usage, not approved by the FDA.


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GENERAL

General

Pilocarpus pinnatus.

Natural order, Rutaceae.

Common names, (Brazilian), Iaborandi, Jaborandi, or Jamborandi. Note This plant is used by the South American Indians as the special antidote to the bite of serpents of the Trigonocephalus group.

Preparation, Tincture of the leaves.

One drop of a solution of the nitrate in the proportion of 1 to 480 was put into the eye. In about twenty minutes the pupils were contracted to the size of a pin's head, without pain or discomfort. Previous to the instillation the patient was barely able to see Snellen's type 4 1/2 at the distance of five feet.

after the contraction of the pupil had taken place, he was able to see easily the same type fully nine feet distant,.

Contraction of the pupil commenced, lasted for twelve hours after all the other effects had passed away (from subcutaneous injections).

from the local application to the eye of one drop of two per cent. solution contraction commenced in ten minutes.

reached its maximum in twenty to thirty minutes, lasted about three hours, and the pupil did not return to its normal size until after about twenty-four hours,.

Myosis caused by local application of the two per cent. solution.

this continued after three or five minutes, and reached its maximum in fifteen or twenty minutes, and continued two or three hours or longer, according to the amount.

during this contraction of the pupils there was but slight change in the refraction of the eye.

the far point approximated somewhat, but was overcome by concave glasses of 1/40 to 1/36.

Atropia Sulphurica Atropia seemed to be a perfect antidote,.

Mist before his eyes (after forty minutes).

he could not see anything on the other side of the ward, a distance of about twenty-five feet, but he could see any one standing by the side of his bed distinctly.

the pupils were not altered from their normal condition (after one hour and ten minutes).

no derangement of vision (after one hour and forty minutes),.

During the sweating and salivation, appearance as of numerous white spots before the eyes like flakes of snow, but without dimness of vision (after twenty-eight minutes). A sort of mist before the eyes.

in spite of wiping the eyes and frequent winking, the sight remained dim and the appearance of snowflakes continued (after thirty minutes). Sight restored suddenly.

no mist, but still some white points moving before the eyes (after forty minutes). Dimness or sight returns, with annoying pricking in the eyes, obliging him to wipe them hard (after fifty minutes). The state of the vision is constantly changing, becoming suddenly more or less dim every few moments (after one hour),.

There was some salivation in all the experiments, and in two cases it was profuse.

but in the lad on whom, two observations were made the effect on the salivary glands was very slight. The salivation was much more profuse in the lad whose skin remained dry. The salivation when it occurred to a marked extent, began simultaneously with the sweating, was greatest when the sweating was most profuse, and lasted as long as the sweating. When the increase of the saliva was but slight, it was difficult to tell when the increase began, or how long it lasted. In the case of the lad who failed to perspire, the salivation became profuse in fifteen minutes, and so continued during three hours and a quarter, and then in a less degree for seven hours,.

Saliva collecting in the mouth (after half an hour).

saliva 3 fluid ounces (after one hour).

increased to 6 fluid ounces (after one hour and a half).

amounts to 8 fluid ounces (after two hours).

10 ounces (after two hours and a half).

saliva 12 fluid ounces (after three hours).

thirteen fluid ounces (after three hours and a half).

14 fluid ounces (after four hours).

salivation had ceased (after four hours and a half),.

Constant spitting of very alkaline saliva (after twenty-five minutes). Salivary secretion extremely active.

submaxillary gland especially enlarged.

on pressing it there is a gush of saliva under the tongue (after thirty-five minutes). On rising, felt weak.

skin still moist, with some flow of saliva. Sat with forehead resting on edge of table, and let saliva run into a vessel on the floor. Remained in this position, the saliva flowing constantly, for an hour and a half (after two hours and five minutes). Tried to sleep, but had to clear the mouth of saliva every two or three minutes (after four hours and five minutes). Flow of saliva entirely ceased (after four hours and thirty-five minutes). Total amount of saliva, 750 cubic centimetres, stringy, but not very viscid,.

Quite a sore throat, smarting pain.

headache, dull pain, mostly on the left side.

breathing hurried. the sore throat and headache lasted all day and evening till I went to bed (twelfth day).

the next morning the headache had gone, but my throat felt so sore that for a time I seriously feared an attack of diphtheria.

it gradually wore off, however, during the day, and the next day I was quite well,.

The pulse curve exhibits at first an increased systolic elevation, a more abrupt curve, a more sudden downfall, and a very decided recurrent elevation.

the artery is filled rapidly and violently, and collapses suddenly.

symptoms of relaxed tone of the vessel and accelerated heart's action.

the character of the pulse-curve is most pronounced after ten or fifteen minutes.

it gradually returns to the normal.

the pulse-curve of a rather rigid and unyielding radial artery in a patient sixty three years old was very interesting.

the elevation was stronger and more vertical, but was not much higher than normal.

the curve did not immediately descend after reaching its highest point, but continued for some time almost horizontal, and then suddenly fell.

the recurrent elevation, which normally could scarcely be noticed, was now very pronounced,.

Tracing No. 1 represents the normal pulse of the subject.

its general aspect is rectilinear, excepting a very slight curve corresponding to a respiratory movement.

the ascending line is short and somewhat oblique.

the descending line nearly horizontal.

the natural dicrotism is well marked. At the commencement of sweat the pulse becomes more rapid, and the tracing assumes a different appearance.

its general outline becomes a little crooked.

the rising line is larger and more upright.

the descending line, therefore, more oblique, with more of the dicrotic character. At the height of the sweating period, the general outline becomes strikingly irregular.

moreover, the beats are no longer isochronous, some being shorter than others. When the morbid activity of the secretory organs had passed off, the general outline becomes regular again, but the ascending line is shorter and more oblique, the descending line longer and nearly horizontal, with hardly a trace of exaggerated dicrotism,.

In each experiment the pulse became considerably quicker, the increase varying from forty to fifth minutes.

the pulse reached its quickest in twenty-five to eighty minutes after administration.

the quickened pulse continued more than four hours.

no close relation existed between the rapidity of the pulse and the fall of temperature.

in one lad whose pulse was intermittent, the medicine entirely removed this irregularity,.

At the moment the sweat was produced, there was an increase of the pulse and of temperature.

then during the period of active sweating, it was sometimes noted that these two elements remained at the same point as at the outset of the experiment.

sometimes there was a slight diminution.

but after sweating, a very notable lowering of the pulse and of the temperature were observed, which sometimes lasted two days after the experiment (in thirty-two experiments),.

Pulse 80 (before taking).

100 (after fifteen minutes).

96 (after twenty minutes).

100 (after thirty-five minutes).

104 (after fifty minutes).

100 (after one hour). 96 (after one hour and ten minutes).

88 (after one hour and thirty-five minutes).

90 (after one hour and fifty-five minutes).

76 (after two hours and five minutes).

78 (after three hours and five minutes),.

Pulse 78 (before taking).

100 (after fifteen minutes).

96 (after twenty minutes).

100 (after thirty-five minutes).

104 (after fifty minutes).

100 (after one hour). 96 (after one hour and ten minutes).

96 (after one hour and a quarter).

90 (after one hour and fifty-five minutes).

76 (after two hours and five minutes).

78 (second day),.

GENERAL SYMPTOMS.

Very soon the face becomes red.

the temporal arteries throb more strongly.

then there is a peculiar feeling of heat in the mouth and on the face, and the flow of saliva begins. In a little while the forehead becomes moist, and the face more red.

then beads of perspiration appear on the forehead, cheeks, and temples. The flow of saliva increases, all the salivary glands successively contributing to this effect.

the mouth is filled with immense quantities of fluid, and expectoration is incessant.

at the same time perspiration covers the face and neck.

then the whole body becomes red and moist, and a pleasant warmth is experienced.

in a few minutes perspiration breaks out over the whole surface, and soon runs down on all sides. Meantime other symptoms have supervened. The eyelids first become moist, then the lachrymal secretion gradually augments, and after collecting in the canthi, rolls slowly over the cheeks.

at the same time there is a copious discharge from the Schneiderian membrane, increased by the tears which escape through the nasal canal.

moreover, there is heightened activity of the mucous glands of the back-throat, trachea, and bronchi. All these effects reach their maximum of intensity in about three-quarters of an hour after taking the drug, continuing thus for thirty or forty minutes. Lying on one side, that the saliva may run more freely, the patient spits ten or fifteen times a minute.

the flow is so rapid that he can scarcely speak.

the salivary glands are enlarged, and the mouth becomes hotter. From time to time the mucous accumulations in the bronchi are cleared away by a slight cough.

the sight is dimmed by the flow of tears. The body is bathed in perspiration.

a shirt is wet through in a few moments. Now, a feeling of comfort, or of weakness, at the case may be, is experienced. Thirst is intense. The pupils are slightly contracted. By degrees the excessive activity of the secretory processes is diminished.

in an hour and a quarter, or an hour and three-quarters, the lachrymation, the nasal discharge, the bronchial expectoration and finally, the flow of saliva, and the perspiration, are sensibly lessened, and the parts involved gradually return to their normal condition. When the perspiration and flow of saliva have ceased, the subject is prostrated and drowsy. The parts which secreted so copiously are now very dry, especially the mouth and back-throat. There is also much thirst,.

Stool at 6.30 A.M., very loose, came with a gush.

stool at 7.30 A.M., stool at 8 A.M., all thin, watery, yellow, and came with a gush.

at 9.30 A.M., another stool.

at 10.30 A.M., another.

at 11.30 A.M., another.

at 1 P.M., the eighth stool.

has felt a goneness, an emptiness, from the diarrhoea, but no pain whatever.

at 3.25 P.M., another stool, which came with a gush, yellow, watery, undigested, no pains.

at 5.25, stool like the last.

at 6 P.M., stool. felt a little weak at night, having had eleven copious, watery, undigested stools since 7 A.M. (twelfth day),.

We noticed an increase of the bronchial secretion, indicated by a loose cough, only in the lad previously quite free from catarrhal symptoms, on whom two observations were made, and in whom but a slight increase of salivary secretion occurred.

the bronchial secretion was much more abundant in the first than in the second observation.

indeed, in the second there was very little cough,.

Perspiration commences later than the salivation by about five minutes, occurring first on the head, gradually extending over the whole body, often with a feeling of intense cold, so that the patient chatters and wishes to be wrapped up.

the duration of the perspiration varies, according to the size of the dose, from one to three hours,.

In each observation a decided fall in temperature occurred. In two cases accompanied by sweating the fall amounted to 1° Fahr., and in another, likewise accompanied by sweating, it reached 2.6°.

but as this observation was begun in the afternoon and continued until the evening, it is impossible to tell the proportion of the fall assignable to the medicine and to the natural diurnal fall, which in children of ten to twelve, usually begins between 4 and 5 o'clock. The reduction of the temperature persisted for the rest of the day, but in the two morning observations the lowest temperature was reached in about one hour and a half after the administration of the medicine. In one case the fall began immediately.

in another case in forty minutes.

in another instance in eighty minutes. In the lad whose skin remained unperspiring, there was a fall of 0.6°, which, beginning forty-five minutes after the administration of the medicine, lasted only two hours and a half,.

In taking his temperature 98.5°, he was obliged to uncover himself, and immediately felt cold, with horripilation and griping in the bowels, as after a purge, but there was no movement. This last symptom ceased in a quarter of an hour.

the chills still sooner, since he again began to perspire most profusely, immediately on covering up (after twenty-five minutes),.

At the moment the sweat was produced, there was an increase of the temperature and of the pulse.

then during the period of active sweating, it was sometimes noted that these two elements remained at the same point as at the outset of the experiment.

sometimes there was a slight diminution.

but after sweating, a very notable lowering of the temperature and of the pulse was observed, which sometimes lasted two days after the experiment (in thirty-two experiments),.

Temperature 37.2° (before taking).

37.4° (after fifteen minutes).

37.5° (after twenty minutes).

37.6° (after twenty-eight minutes).

37.5° (after thirty-five minutes).

37.4° (after fifty minutes).

37.4° (after one hour).

37.2 (after one hour and ten minutes).

37.1° (after one hour and a quarter).

36.3° (after one hour and fifty-five minutes).

36.3° (after two hours and five minutes).

37.2° (second day),.

Moisture on the forehead (after half an hour).

perspiration over entire body (after one hour).

still free (after one hour and a half).

perspiration chiefly on face, legs, and feet (after two hours).

perspiration continues (after two hours and a half).

diminished amount of perspiration (after three hours).

less (after three hours and a half).

skin merely moist (after four hours, and four hours and a half),.

Commencement of sweat (after fifteen minutes).

forehead covered with sweat.

body still dry (after twenty minutes).

commencement of general sweat (after twenty-five minutes).

sweat copious (after thirty-five minutes).

at its maximum (after forty minutes).

begins to decline (after one hour).

much diminished (after one hour and thirty-five minutes).

no sweat (after two hours and five minutes),.

Skin of forehead a little moist (after fifteen minutes).

perspiration begins to show in drops on forehead, rest of body moist (after twenty minutes).

general sweat commences (after twenty-eight minutes).

copious sweat all over (after thirty-five minutes).

sweat at its height (after fifty minutes).

appears to be diminishing (after one hour).

going off (after one hour and ten minutes).

sweat almost over (after one hour and fifty-five minutes).

no sweat (after two hours and five minutes),.

In three instances the drug produced perspiration.

one lad's skin remained quite dry throughout the experiment. In two of the lads perspiration set in in from ten to fifteen minutes.

in the third case it was delayed for thirty-five minutes, becoming profuse in from twenty to thirty-five minutes, and continuing thus from thirty minutes to one hour and a half, and then remaining slight from two to four hours and a half,.

The dilatation of the vessels began after two or three minutes, and lasted from half an hour to an hour, accompanied by redness of the skin, and soon followed by perspiration.

there was speedily noticed a decided swelling of the bloodvessels of both the arteries and veins.

the temporal artery, which before the injection could scarcely be noticed, became a thick prominent cord, with visible pulsation.

its diameter doubled. at the same time the veins in the forehead became swollen and appeared as large blue vessels, so that as the perspiration began the patient had the appearance of one excessively heated.

the same dilatation is noticed in the radial arteries.

the veins on the forearm and hand frequently seemed swollen.

the pulse was fuller and more rapid, sometimes decidedly dicrotic.

the pulse rose from 80 to 100, or even 120,.

Before the injection, temperature 24.7, pulse 104. The drug began to exhibit its effects in forty-five minutes, when the face and chest became red, and covered with slight perspiration.

five minutes later the whole body was covered with profuse sweat, together with copious salivation.

temperature 37.1°, pulse 100. The salivation and perspiration lasted about five hours, after which the patient was very thirsty, but in other respects well,.