Physostigma - Eyes symptoms - T.F. Allen

EYES

Eyes

Left eye was red and swollen (fourth day),

Right eye first inflamed, then the left; sclerotic red, dry, and swollen; eyes feel best when closed,

Burning of eyes, and bloodshot appearance of them, all the forenoon (eleventh day),

His father stated that "his eyes were working," or as his mother said, "as if the nerves were upon him,"

(Eyes unusually free from black spots, in the morning), (second day),

Eyes very dull and heavy, at 2 P.M. (fifth day),

Eyes heavy,

Eyes sleepy-like,

Continued drawing twisting sensation in the eyes (thirteenth day),

Sharp shooting and drawing sensation in the right eye, at 1 P.M. (fifth day),

Drawing twisting sensation in the eyes, at 3 P.M. (fifth day),

Since 11 A.M., have had great drawing twisting sensation in the eyes, at 8 P.M. (tenth day),

Drawing sensation in the eyes, at 6 P.M. (third day),

Eyes are sore, and give pain when moved from side to side, at 6 P.M. (second day),

Eyes smart; lids feel sore (third day),

(Was asked by a physician if I do not suffer from diplopia, as the musc. int. seems not to do its work rightly, and the axis of the eyes differs in each; but my eyes only felt weak, with lachrymation, especially of left eye, from which I suffer when having my usual headaches), (sixth day),

Slight aching pain in left eye (after five hours),

Felt film over the eyes, and blur; objects mixed (after ten minutes); after which dull pain over the eyes, and between the eyes, lasting for one hour; sometimes have had similar feelings, but not often,

Pain in the left eye, with muscae volitantes,

Eyes feel weak (third day),

Eyes sensitive (eighth day), and feel weak (ninth day),

Had the symptoms in the eye all the morning, with much burning of the balls (sixth day),

Orbit.

Aching pain in posterior part of orbit, extending back into the brain; worse on reading (aches so cannot read), causing nausea (second day),

Lids and Lachrymal Apparatus.

Twitching of upper eyelids, at 4 P.M. (fifth day); of left most, which is very annoying (seventh and ninth days),

When the accommodation becomes affected by Physostigma, twitchings (spasmodic) of the lids ensue,

Sensation of contraction of the eyelids, with difficulty of opening them, and a suffusion of tears when wide open (after fifteen minutes); it required and effort to keep the left eyelid open; this lasted till night, with pain in right side of upper jaw (second day),

Cannot bear to raise the lids (sixth day),

If Physostigma is applied to the lids it produces immobility of them,

Eyelids feel heavy (second and fourth days),

Lids, which are usually heavy, were less heavy, and can look more steadily at an object; but lids grow heavier again later,

At night, intense itching of the edges of the eyelids and inner canthus of the right eye (sixth day),

Eyes suffused with tears (after seven hours and a half, second day),

Ball.

Pain in the eyeballs (third day),

A drawn, twisted sensation in the eyeballs, at 8 P.M. (second day); especially in the right, at 7 P.M. (third day),

Towards the end of the myotic action there is experienced a painful tension, partly in the equator of the ball, partly in the ciliary region,

Great fulness of the eyeballs, as if they were too large, with a sensation as if the lids were too tight on closing them (first night),

Swollen sensation, with burning in the eyeballs (third day),

Nervous achings in the whole ball, which extended along the supraorbital nerves, and over half the head,

The circulation in the fundus of the globe is not affected,

Pupil.

Decided dilatation of the pupil, very soon,

Pupils dilated (third day),

After the myosis had passed off there is usually mydriasis of a slight degree for several days, especially during the morning hours; this seems to depend upon a kind of fatigue of the sphincter, which passes off during the day under the reflex stimulus of light,

A very slight dilatation of the pupil was perceived,

The myotic effects of the extract began to be noticed after fifteen to thirty minutes; the maximum contraction was obtained in from thirty to forty minutes; the myosis continued stationary from twenty minutes to three hours; the action of the drug was limited to the eye to which it was applied,

Pupils contracted (fourth, fifth, and sixth days); very much contracted (eighth day),

Pupil very much contracted (after one hour),

Pupils contracted (second day), ; (second morning), ; (fourth and eighth days),

In about two-thirds of the cases the pupils were contracted, and there was double vision,

Pupils slightly contracted,

Accommodation.

The action on accommodation consists in the approximation of the far point (myopia), and also of the near point; this contraction does not usually progress steadily, but by spasms or jerks (just as the pupil contracts); the far point is approximated sooner than the near point,

Daturin paralyzes accommodation and dilates the pupil like Atropine, but Physostigma introduced after Daturin restores the accommodation and produces strong myopia, while the pupil is still widely dilated,

The accommodation recovers before the pupil,

The phenomena of the accommodation lasts much shorter than does the myosis. The approximation of the near point lasts longer than that of the far point,

Vision

Can see farther than usual (is naturally myopic), (second day),

Double vision,

Visual acuteness often sinks to one-half the normal under its use,

One observer could bring his vision with perfect clearness to the normal, but only with very great and painful exertion,

Dimness of vision (after sixty minutes),

Sight bad at all times; rather dull; clouds passing over the sun interrupt his walking (second day),

For the last three days he has had attacks of partial blindness; on attempting to write he was unable to see the line (sixth day),

Letters seem in constant motion, and can only be seen at a large visual angle,

Bright daylight seems like twilight, the result of the largely contracted field of vision,

Vision seemed hazy or misty, while walking; better at once by keeping quiet (fourth day),

Bright marks when looking at an object; dark-yellowish spots on book when reading, covering one or two of the letters,

Muscae volitantes, both black and white (tenth day),

Had muscae volitantes very much (fourteenth day),