Below are the main rubriks (i.e strongest indications or symptoms) of Physostigma in traditional homeopathic usage, not approved by the FDA.
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Eruption upon the back about the size of fleabites; the same petechial eruption on the arms (fourth day),
Fever blisters in and around left nostril (seventh day),
Applied to the skin it benumbs, and causes a pricking all over the spot,
Itching of the left palm (fourth day),≡ more ...