Please Help for Severe Chronic Pain

Thank you. I also forgot to add that she has had a piece of bone removed from her right hip and placed in her neck to fuse it.
The herniated disks in her back have been present since she was 16 after a car accident. She is now 45.

She has sciatica in her right leg and her tendons and ligaments were completely torn in her right ankle when she was 6.

Could Hypericum be used in conjunction with the Bryonia?

The swelling in her knee went down slightly this morning, but is more painful.

She is still losing weight rapidly without intending to.

Would a small fast be beneficial before beginning the remedy or can I give it to her today?

Thank you so very much again.

Also, would her daily 'western meds' cancel out the remedy?

Her prescription painkillers are no longer reducing the inflammation, and are just barely taking the edge off her pain. She would like to eventually be completely off her medications, and is working on reducing her coffee consumption. I have begun switching her over to herbal teas and Rescue Remedy Energy spray.
She is now down to only 3 cigarettes a day and is determined to quit entirely as soon as possible.

Thanks!

As I have been spending more time with my foster mom, I am learning more about her chronic physical problems. She almost never complains and continues to do her daily routine and is as physically active as her body and pain level allow her to be. She frequently pushes herself beyond what she should be doing and just silently deals with the pain.

For a number of years, she has also been getting vitamin B12 injections and was diagnosed with Pernicious Anemia. Is there any remedy that could be taken to address the anemia and her stomach's inability to produce intrinsic factor?

Update:
There has been a little change in her knee swelling and she says the pain isn't quite as intense.

Is there another remedy we could use with the Bryonia?

Okay, will do. Thanks!

Her case is really puzzling me because there is so much that is chronically wrong and she has been diagnosed with so many different things. All of which are degenerative and have no known cure with conventional western medicine. She said she was near normal up until the car accident that injured her back and neck when she was 15/16. She did not have the injuries addressed until 3 years later.
There is a history of childhood abuse, so I am thinking that may have a part in her body's state today.
I wish there was a reputable homeopath nearby that would be able to help with curing my mom.

She was just able to do the Phosphorous over the past 2 days.
Finally got her off the caffeine and the prescription amphetamines. Last night, she was exhausted and ready to go to bed very early, but then took her last dose of the Phosphorous and perked up, seemingly having a big change mentally. This morning she had energy for the first time in years, and stated that she did not know why she just felt good this morning. Almost no hint of depression.
Her knee is doing MUCH better, she said there is almost no pain at all and the fluid/swelling is completely gone. (this marked improvement was seen after the Bryonia and before the Phos.)

This week, she is making a major move that she is dreading (back to a childhood home where she was the victim of and witnessed abuse, but her terminally ill mother wants to return) and I am worried about the knee pain returning and the back pain intensifying.

Her neck and back haven't had much improvement, but she is doing work and lifting heavy objects that she really shouldn't be. All of the help she was promised by other people has not happened and her son has decided that he is not going with her.

Her hands are no longer burning hot, and they have instead become cold (like she said they were in childhood), but she is experiencing tingling in her extremities that she claims is from the injury to her spine and the muscle tension/spasms cause by the herniated discs.

Is there a next remedy we should try?

Thank you in advance!