high uric acidsir,
i am suffering from high uric acid. my uric acid is 7.
can i take colchicum 30? if yes, what will be the dose.
ashwani4877 on 2008-08-14
Ideal is to controll it through diet,i.e. mainly avoid animal protein.
Also read these notes carefully :-
What is uric acid?
Uric acid is a waste of protein metabolism. It is also present in large quantities in some foods. It causes problems because humans do not possess the enzyme to digest it to a soluble form. When uric acid precipitates it can cause kidney stones or gout. Gout is a problem where uric acid crystals deposit in the joints, causing a painful inflammatory response.
How does uric acid levels increase in our blood and what precautions can be taken to avoid it? Uric acid is a waste product in our body and is eliminated by our kidneys. Uric acid is produced from the breakdown of a certain kind of a substance known as purine. This substance also produced in our body and is also present in some of the food that we eat. Uric Acid increases due to mainly three conditions? firstly if there is an over production of uric acid in our body(some situations like fasting, strenuous exercising and crash dieting)., secondly if there is a decreased removal of uric acid by the kidneys; thirdly if one takes excess amounts of food which are high in purine.
How do uric acid stones form?
Like any stone, uric acid stones form when too much uric acid is present in the urine to remain dissolved. Uric acid stones form quickly as there are no known inhibitors in human urine to cope with fluctuation in output. A short period of dehydration in a susceptible individual is enough to begin stone formation. A sudden uric acid load from food can also precipitate a new stone. This means that what you eat and drink directly affects your chance of developing stone.
So what do I do?
Drink enough - You need to pass a pale urine consistently. Because stones form quickly, a single hot day working in the garden could lead to a stone. Aim for the colour below;
Watch your diet - diet will have a major effect. Ask anyone who gets gout and they will be able to tell you which foods can trigger an attack. There are two aspects to diet control. One is the acid in the diet, and the other is the concentration of uric acid in various foods;
Acid from food
Uric acid's solubility in urine is dependent on the pH, or acidity of the urine. At a pH of 7 (neutral), urine can dissolve 1000 times the amount of uric acid than at pH 5 (acidic). Most people who form frequent uric acid stones have an acidic urine. Urine becomes acidic in response to diet. Proteins are the greatest source of acid in the diet. After a meal high in protein conditions become ideal for stone formation. So avoid eating large amounts of meat at one sitting and drink plenty of fluids with your meal. Adding some foods which have an anti-acid effect into the meal can also help. Dairy products are foods of this type. If you are particularly at risk taking a one off dose of the alkalinization agents below can also help.
Do you have high uric acid levels in your blood? If so then there are chances that if it goes unchecked you might end up suffering from Gout. Gout is a disease that affects the joints .This disease in earlier days was also called as the ?disease of the kings ?because it was associated with overindulgence in drinks and rich food.
But it is not so nowadays, it can strike anyone; men being more at risk than women.
Foods high in purines which should be avoided by those who are having levels of uric acid are ? quite a few of the non vegetarian food, lentils (dals), whole grains, peas, cauliflower, and mushroom. Alcohol intake slows down the removal of uric acid. Being overweight also adds to the increased levels. A simple blood test (serum uric acid) at a local lab can be good enough for an evaluation.
What is Gout and how does a high level of uric acid in blood lead to gout? Gout is an inflammatory condition of the joint .Gout results in an inflammation of the joint. This is due deposition of uric acid crystals in the joint spaces and or in the connective tissue of the joints. It is a very painful condition causing swelling redness heat pain and stiffness of the joint. Deposits of uric acid, called tophi can appear as lumps under the skin around the joints. Gout mainly affects the big toe but it can affect other joints like gout instep, ankles, heels, knees, wrists, fingers, and elbows
Increased uric acid is not a disease and by itself is not dangerous. However, if excess uric acid levels lead to formation of crystals between the joints, gout can develop. In some individuals excess levels also lead to formation of kidney stones. Please remember not all who have high levels of uric acid, develop gout.
Uric acid is the only true measure of whether you are dealing with your gout. There is a common tendency amongst gout sufferers (which I must admit to myself) to treat short term discomfort and forget long term urate build-up.
This is a bad thing. Uric acid crystals can build-up slowly in tissue without major pain attacks. Suddenly you notice strange jelly-like swellings that slowly grow and get harder until they either burst through your skin or permanently cripple your joints. These are called tophi, and they are not nice.
Foods High in Uric Acid
Studies have shown that foods high in uric acid play a major role in the development and aggravation of diseases such as gout. In conjunction with a healthy lifestyle and changes in diet, it can actually be easier to manage than many people believe, as long as the sufferer is willing to make some significant changes in their eating habits.
Gout is a painful disease that is most common in men, especially older men, but can also affect women. It is caused by a condition called hyperuricemia, which means that there is actually too much uric acid in the blood. While uric acid is actually a waste product left over from metabolism of chemical compounds called purines, it can also be found in some foods and alcohol.
Diets to reduce uric acid are extremely helpful in lowering levels of uric acid in the body, and will usually involve reducing or cutting out foods that have high levels of purines.
Normally, uric acid is eliminated from the body by the kidneys and a bit of hyperuricemia usually does very little harm. In fact, most people with high levels of uric acid in the blood never develop gout. However, some people are more sensitive to high levels of uric acid, and their bodies will form crystals that accumulate in the joints and cause painful gout symptoms.
The main goals of treatment for gout are relieving the chronic pain that comes with this disease as well as prevention of future gout attacks. Left untreated, it can also lead to long term problems like joint destruction and, ultimately, kidney damage. Diets to reduce uric acid also benefit gout sufferers by helping them lose weight, which has also been shown to help lower concentrations of uric acid in the blood.
Foods containing uric acid and the compounds that metabolize into uric acid include most animal meats, such as beef, pork and seafood. Poultry and ham, the 'white meats,' can have some degree of purine content and should be eaten very sparingly, but they are not as detrimental as the 'red meats.' Bacon, however, is very high in purines due to the processing used to make it ready for human consumption and should be avoided. Alcohol and breads which contain yeast are also foods high in uric acid that should be kept out of the diet.
Black cherry juice, also known as sour cherry or bitter cherry, is also being used in great quantities to help relieve the symptoms of gout in conjunction with diets to reduce uric acid. Celery seed extract and bromelain are some popular alternative medicine remedies that have been used as natural anti-inflammatories and have been well received by those who suffer chronic inflammation. Adding eicosapentaenoic acid (EPA) and folic acid to the diet can also assist in reducing inflammation in gout episodes.
By eliminating some foods high in uric acid from the diet, many gout sufferers have found some measure of relief from their pain and taken back control over their bodies that they feel had been taken away from them. Diets to reduce uric acid are also quite beneficial in conjunction with other natural therapies such as heat therapy and acupuncture, and many people are reporting a definite decrease in pain and other symptoms simply by making a few changes to their diet and lifestyle.
What to eat?
Eat foods low in saturated fat, such as:
Fat free or 1% fat dairy products skimmed milk
Fish and shellfish in limited quantity & Lean meats
Whole grain foods
Certain fruits (e.g. apples, pears & guava)
Certain vegetables (e.g. cabbage, green leafy and carrots less spinach)
Dried peas and beans. Dry peas and beans also have a lot of fibre, which can help to lower blood cholesterol. Try adding a ½ cup beans to pasta, soups, and vegetable dishes.
Egg whites have no cholesterol, and you can substitute them for whole eggs in recipes - two egg whites are equal to one whole egg.
Buy low fat dahi (curd) or make it at home using only skimmed milk. Try topping it with fruit.
Choose liquid vegetable oils that are high in unsaturated fats - like canola, corn, olive, peanut, safflower, sesame, soybean, and sunflower oils.
Choose whole grain breads. They have more fibre than white breads.
Strawberries and cherries have great benefit in reducing uric acid the cherries can either be fresh or tinned and has been hailed in numerous natural therapy books. I hope this is of use to you.
What not to eat?
Limit foods high in cholesterol, such as:
liver and other organ meats
Egg yolks. Yolks are limited to no more than 3 yolks per week
Full-fat dairy products , whole milk etc.
Limit butter. It is high in saturated fat and cholesterol.
Limit sweet baked goods that are made with lots of saturated fat, mostly from butter, eggs, and whole milk such as croissants, pastries, muffins, biscuits, butter rolls, and doughnuts. These are also high in cholesterol.
Limit foods high in saturated fat, such as:
High fat processed meats (e.g., sausage, kheema) and fatty, untrimmed red meats.
Other Defensive Measures
Alcohol, especially beer, should be avoided. Limit alcohol consumption to 1 drink 3 times a week. Alcohol increases uric acid production by accelerating purine breakdown. It also reduces uric acid excretion by increasing lactate production, which impairs kidney function. Elimination of alcohol is all that is needed to reduce uric acid levels
Drink 2 to 3 L of fluid daily. Adequate fluid intake helps dilute urinary uric acid.
Avoid acid forming items like artificial sweeteners, Carbonated soft drinks & fizzy drinks, Cigarettes, Flour (white wheat), Goat, Lamb, Pastries & cakes from white flour, Pork, Sugar, Beer, Brown sugar, Chocolate, Coffee, Custard with white sugar, Jams, Jellies, Liquor , Pasta, Semolina, Table salt(refined & iodised), Tea black, White rice, vinegar.
Avoid High-Purine foods like organ meats, whole eggs etc
Consume a moderate amount of protein. Limit meat, fish and poultry to 4 - 6 oz per day. Use preferably good protein food such as low fat dairy products and soy protein.
Limit fat intake by choosing leaner meats, foods prepared with less oils and lower fat dairy products.
50% of the uric acid in the body comes from food. Below is a list of food high in uric acid;
Shellfish Lobster, crayfish, prawns, mussels, oysters, crabs, scallops.
Organ meats Liver, kidney, brains, sweetbreads
Red meat Any red meat. Especially game.
Vegetables Peas, beans, spinach
Fish Anchovies, mackerel, sardines, herring
As previously stated, the solubility of uric acid is pH dependent. If your urine is acidic (pH 5) it will dissolve a thousand times less uric acid than at pH 7. Alkalinization is usually reserved as a treatment to dissolve away stones that have already formed. Either bicarbonate of soda or citrate are used. The aim is to raise the pH of the urine to the range 6.5 - 7. The amount of citrate or bicarbonate required varies from person to person. You will be asked to monitor the acidity of the urine with a simple dipstick test. When you know how much to take you should remain on his dose until the stone has gone. It is important not to take too much as raising the pH over 7 increases the risk of calcium stones forming. Remember, water has a pH of 7 so, the more you drink, the more likely you are to achieve the right level of acidity.
It is not unreasonable to take a dose of citrate or bicarbonate after a meal high in uric acid. This should not be seen as an effective way to eat lots of shellfish and brains
Drink enough water & Limit your protein intake
Increase output of uric acid
Ingestion of 500 mg of Vitamin C per day has been shown to bring about a 0.5 mg/dl decrease in serum uric acid through increased excretion. Some Gout sufferers have recently found that taking up to 1,000 mg of Vitamin C, combined with a small dosage (approx. 10-15 mg./day) of Lithium have had very beneficial effects on their uric acid levels.
Vitamin C, taken in high doses, can help decrease blood uric acid levels, but should not be taken without a doctor's supervision. Note that there is a small subset of people with gout who will actually get worse with high levels of vitamin C. Also, a single high dose can free up too much uric acid and cause kidney stones. (University of Maryland Medical Center for Integrative Medicine). Avoid aspirin.
Foods High in Purines Food (Total Purines in mg uric acid/100 g) Fish, sardines in oil (480) Liver, Calf's(450) Beef, (110) Fish(257) rispbread(60). Meat, poultry, nuts, seeds, eggs and seafood are all fairly high in purines.
znaeem51 last decade
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