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BoooBooo : Diabetes Mellitus - Miasmatic Background & Treatment

Diabetes mellitus is a disease which is known to everybody nowadays. It is to be noted with astonishment that DM has an attracting global importance as it is rocking the world as a non-infectious epidemic/pandemic. “SUGAR” is the common name given to DM by the Indian layman. Actually, it comprises a group of common metabolic disorders that share the phenotype of hyperglycemia (increased level of glucose in blood plasma). Nowadays, it is one of the leading causes of morbidity and mortality because Diabetes mellitus causes secondary pathophysiologic changes in the multiple organ system. Most likely, the complications of DM are adult blindness; non-traumatic lower extremity amputations (diabetic foot); end stage renal disease (ESRD); neuropathy etc. In the forecoming days it is presumed to be increasing day by day due to an increase in factors contributing to hyperglycemia, which may include dietetic irregularities, metabolic dysfunction, lack of exercise, stress, and busy lifestyle. As concerned about the cure of DM by Homoeopathy, it could be possible in the early stages but we can at least assure to give a peaceful and prolonged life to a diabetic patient.

Recent studies in the etiologies and pathogenesis of Diabetes mellitus lead to a revised classification. Recent changes in classification reflect an effort to classify DM as the basis of the pathogenesis process leading to hyperglycemia, as opposed to criteria such as age of onset or type of therapy. Some forms of Diabetes mellitus are characterized by an absolute insulin deficiency or a genetic defect leading to defective insulin secretion, whereas other forms share insulin resistance as their underlying etiology. Diabetes mellitus has two broad categories designated as type1 and type2.

TYPE 1 Diabetes mellitus (previously designated as IDDM): Type 1 DM is categorized into two subgroups, i.e., type 1A and type 1B. Type 1A results from autoimmune ß cell destruction, which usually leads to insulin deficiency; where as type 1B DM occurs due to lack of immunologic marker inductive of an autoimmune destructive process of the ß cells. Type 1 DM is hereditary in character and develops before the age of 30 years. The patient is young, lean and thin, and has an absolute requirement for insulin therapy.

TYPE 2 Diabetes mellitus (previously designated as NIDDM): Type 2 DM is characterized by a variable degree of insulin resistance, impaired insulin secretion, and increased glucose production. Type 2 DM more typically develops with increase in age; it also occurs in children, particularly in obese adults. It does not require insulin therapy.

GDM: This type of Diabetes mellitus is recognized during pregnancy. It is due to insulin resistance related to its metabolic changes.

MODY: It is a subtype of Diabetes mellitus is characterized by autosomal dominant inheritance, early onset of hyperglycemia and impairment in insulin secretion. It is also divided into MODY1, MODY2, MODY3, MODY4, and MODY5 according to genetic defect of beta cell function characterized by mutation in Hepatocyte nuclear transcription factor (HNF), glucokinase, HNF1 a, insulin promoter factor (IPF), HNF1 ß.

OTHER CAUSES:

• Drug or chemical induced Diabetes mellitus: Some drugs such as Nicotinic acid, Glucocorticoids, Thyroid hormones, Diazoxide betaadrenergic agonists, Thiazides, ß blockers etc causes DM.
• Endocrinal Diseases: This includes Hyperthyroidism, Hypersecretion of Adrenal cortex, Hyperpituitarism, Cushing’s syndrome, Pheochromocytoma, Acromegaly, Somatostatinoma.
• Diseases of Pancrease: This includes Pancreatitis, Cystic Fibrosis, Hemochromatosis, Pancreatopathy, Cancer of pancreas, Pancreactectomy.
• Other Genetic Syndrome sometime associated with DM like as Down’s syndrome, Klinefelter’s Syndrome, Turner’s syndrome, Huntington’s corea.

RISK FACTORS FOR TYPE 2 Diabetes mellitus

• A strong family history
• Obesity
• Age = 45 years
• Previously identified IFG or IGT
• History of GDM
• Hypertension (Blood pressure = 140/90 mmHg)
• HDL cholesterol level = 35 mg/dl
• Triglyceride level > 250 mg/dl
• Polycystic ovarian syndrome


EPIDEMIOLOGY

The prevalence of Diabetes mellitus in adults was 4 percent worldwide; this means that over 143 million persons are now affected. It is projected that disease prevalence will be 5.4 percent by the year 2025, with global diabetic population reaching to 300 million. The rising prevalence of Diabetes mellitus in developing countries is closely associated with industrialization and socioeconomic development. Diabetes mellitus, a chronic disease once though to be uncommon in the developing world has now emerged as an important public health problem in Asia. An estimated 30 million persons in South-East Asian region are affected at present. It is estimated that by the year 2025 there will be nearly 80 million diabetics in the region- the highest among all WHO regions. Thus, the South-East region will bear the maximum global burden of the disease. The result of prevalence study of DM in India was systematically reviewed with emphasis on these utilizing the standard WHO criteria for Diabetes mellitus diagnosis. The prevalence of disease in adults was found to be 2.4 percent in rural and 4-11.6 percent. This indicates the potential for further rise in prevalence of DM in the coming decades. It is estimated that during 1997 about 102,000 persons died of DM in India with about 1,981,000 DALYs.

PATHOGENESIS

The pathogenesis of each type of Diabetes mellitus is different and discussed separately.

TYPE 1: This type of DM is characterized by an absolute lack of insulin, which is why patient always wants insulin. It is previously called as IDDM. The absolute lack of insulin is due to the beta cell destruction. There are three main mechanisms responsible for beta cell destruction that is genetic susceptibility, autoimmunity, and environment insult. These factors of genetic predisposition and environmental insult causes unnecessary immune response against normal functioning beta cells. This immune response triggers the auto immunity, which causes beta cell destruction. When complete destruction of beta cells occurs, no insulin secretion occurs in the bloodstream that causes type 1 Diabetes mellitus.

TYPE 2: Type 2 Diabetes mellitus is characterized by decrease in beta cell secretion of insulin or a decrease response of the tissues to respond to insulin, i.e. insulin resistance. The main factor involved in the pathogenesis of type 2 Diabetes mellitus is environmental factor. Obesity is one of the most important cause although genetic predisposition is also important which causes deranged insulin secretion and cause hyperglycemia. This hyperglycemia causes ß cell exhaustion and decrease in insulin secretion. Other metabolic disturbances cause reduced responsiveness of tissues to insulin action called as insulin resistance. It is a major factor in the development of type 2 Diabetes mellitus.

Gestational Diabetes mellitus (GDM): GDM is a prodromal form of type 2 DM being unmarked by pregnancy. Pregnancy is associated with insulin resistance that necessitates an increase in insulin production to maintain euglycemia (a normal insulin concentration of glucose in blood). Placental hormones that rise late in pregnancy induce the insulin resistance in GDM. Gestational Diabetes mellitus itself is typically found late in the second or early third trimester. Some studies suggest that there is an exaggeration of the pregnancy induced insulin resistance in GDM, but it appears that the major determinant of whether a woman develops DM is likely insulin reserve. This reserve is blunted in women with GDM. In severe GDM an element of glucose toxicity supervenes which may further blunt the insulin sensitivity. The elevated free acids that are also found in GDM may be a further cause of insulin resistance as may be a manifestation of the disease process itself. Thus, GDM is similar to type 2 DM with insulin resistance and impaired insulin secretion, and persistence of these abnormalities postpartum contributes to the increased risk of type 2 DM in the long term.

DIAGNOSIS

New revised criteria for the diagnosis of DM from the expert panel of WHO and National Diabetes Data Group emphasize the FPG as the most reliable and convenient test for diagnosing Diabetes mellitus in asymptomatic individual.
Glucose tolerance is classified in to three categories based on the FPG
• FPG < 110 mg/dl is considered as normal
• FPG = 110 mg/dl but < 126 mg/dl is defined as IFG (Impaired Fasting Glucose)
• FPG = 126 confirm the diagnosis of DM

IFG is a new diagnostic category analogous to IGT, which is defined as the plasma glucose level between 140mg/dl and 200mg/dl, 2 hour after a 75gm oral glucose load.

A random plasma glucose concentration = 200 accompanied by classic symptoms of Diabetes mellitus, for example polydipsia (increased thirst), polyuria (increased micturation), polyphagia (increased appetite), weight loss is sufficient for the diagnosis of DM.

The two-hour plasma glucose commonly referred to post parendial is still a valid mechanism for diagnosing DM but is not recommended as a part of routine screening.

MIASMATIC BACKGROUND

Diabetes mellitus comprises the pseudopsoric miasm. The pseudopsoric miasm is also known as Tubercular miasm. It is a combination of both Psora and Syphilitic miasm. Tubercular miasm is usually characterized by a “problem child” i.e. slow in comprehension, dull, unable to keep a line of thought, unsocial, morose. He/she gets relief from offensive foot or axillary sweat which when suppressed often induces lung troubles or some other severe disease. The patient's mental symptoms tend to be ameliorated by an outbreak of an ulcer. The slightest bruise suppurates; the strong tendency is to the formation of pustules. As a general rule, the patient is very intelligent, keen observer and a programmatic planner who wants his life always busy but possesses a sedentary lifestyle.

INDICATION OF MIASM

As the miasm progress and predominates, weight loss, depreciation and destruction are the first indication of this miasm. Other indications are cosmopolitian habits, mentally keen but physically weak. Symptoms are ever changing. Rapid response to any stimuli (e.g. any slightest change of weather or atmosphere). Emaciation instead of taking proper diet and drink, tendency to cough and cold easily, desire and craving for unnatural things to eat, with desires and cravings for narcotics such as tea, Coffee, tobacco and any other stimulants have often their origin in psoric or tubercular miasm. They sometimes have constant hunger and eat beyond their capacity to digest or they have no appetite in the morning but hunger for other meals.

COMPLICATIONS OF Diabetes mellitus

The complications of Diabetes mellitus are categorized into two main groups i.e. Acute and Chronic complications. The acute complications are due to metabolic disturbances. These include DKA (Diabetic Ketoacidosis) and Nonketotic Hyperosmolar state.

The chronic complication are also categorized into two broad groups

1. Microvascular complications: These include Ophthalmic Disorders (Retinopathy, Macular edema, Cataract, Glaucoma), Neuropathy (Peripheral neuropathy, Sensory and Motor polyneuropathy), and Nephropathy (ESRD).
2. Macrovascular complications: These include Coronary Artery Diseases (CAD), peripheral vascular disorders, and cerebrovascular diseases.
3. Other complications include Gastroparasis, Diarrhea, Uropathy, Sexual dysfunction and Dermatologic complications like eczema, cellulites, and gangrene of distal part of limbs (Diabetic foot).

MISAMATIC DISCUSSION ON COMLICATIONS OF Diabetes mellitus

DM has a psorosyphilitic background. As the syphilitic miasm becomes predominant the complications arise. The acute complications are of the psoric character because they have metabolic disturbances while the chronic complications are associated with syphilitic background or as a result of a mixture of two. As the strong syphilitic character is going to destruction and degeneration it leads to mixed miasmatic diseases. These diseases are more difficult to cure especially when they go to irreversible changes. When the syphilitic miasm is dominant in the condition of chronic complications the condition should become violent. At this stage the individual needs a complete Miasmatic and Therapeutic treatment.

MANAGEMENT

Before we are going to start treatment of DM, it is very essential to know about proper nutrition and exercise plan for diabetic patient to reduce the prevalence and incidence of complications. It must also include preventive plan for an individual.

• Diet and Nutrition plans
• Exercise plans

DIET AND NUTRITIONAL PLAN:

Proper nutritional management or food plan is essential for better glucose control. This in turn helps to reduce the risk of diabetic complications. Daily consistency regarding the types of food including in the meal, their nutritional information, and the time at which they are consumed will help to normalize the blood glucose levels.

The common meal planning tips are:

• Avoid saturated fats and oils; instead of that use unsaturated oils found in olive oil, nuts, and canola oil
• Moderate salt and salty food consumption, especially when high blood pressure is present.
• Watch the amount of protein-rich food.
• Incorporate high-fiber food such as grains, raw vegetables and fruits (fruit is better than the fruit juice).
• Spread your daily carbohydrate intake through the day. Don’t eat too much carbohydrate at any time.

EXERCISE PLAN:

Physical activity is recommended for everyone. It should take place any time when a person can and is willing. The minimum time recommended is about 30 minutes; three or more times a week. Activity can include moderate walking and household chorus, such as gardening and cleaning as well as jogging, biking, dancing and other sort of exercises.

When starting an exercise plan, be sure to warm up, set a comfortable pace, wear good shoes and drink plenty of water. Make it as enjoyable as possible without overdoing it. A good partner will make it easier to commit to it. Be cautious with the duration and intensity of the exercise; then gradually increase the length of the activity by a few minutes every week.

WHEN NOT TO EXERCISE:

• If you are ill.
• In extreme heat or cold.
• During peak insulin action times.
• If your blood sugar is high exercise will usually help bring it down; but if your blood sugar is over 250mg/dl do not prefer exercise.

TREATMENT

As Homoeopathy is not a science of therapeutics, it is concerned with totality of symptoms or individuality. As regarding the cure of DM by homoeopathic medicine, the individual needs the complete miasmatic and constitutional therapy in the very early stage.

MIASMATIC TREATMENT:

If we are going through complete miasmatic study of the individual in early stages then we can easily find out about the disease for witch an individual is prone to suffer. Then, we can apply the antimiasmatic therapy as a preventive measure which causes a decline in the tendency for the progression of the miasm.

THERAPEUTIC TREATMENT:

Acetic acid (Glacial acetic acid) 6, 30: Large quantity of pale urine, unquenchable thirst, and great debility.
Abroma augusta (Olatkambal) ?, 2X, 3X: Frequent and profuse urination, dryness of the mouth and great thirst, urination leads exhaustion, Fishy odour of the urine, Diabetes mellitus and insipidus.
Argentum metallicum (Silver) 6, 30, 200: Polyuria, frequent urination, urine profuse at night, turbid and sweetish odour, restless sleep, frightful dreams, edematous swollen feet, flatulent distention of abdomen.
Arsenicum album (Arsenic trioxide) 6, 30: Urine scanty, burning albuminous, ascites, all prevailing debility, restlessness, burning thirst, drinks often but little at time.
Codeinum (An Alkaloid from Opium) 3X, 3: Sugar in urine, quantity of urine increased, great thirst, it is said to control disease.
Cephalandra indica (Telakucha) ?, 1X, 3X: DM and insipidus with profuse urination; weakness and exhaustion after urination; sugar in the urine.
Gymnesa sylvestre (Meshasringi or Gurmar) ?, 3x, 6: Is almost specific for DM called as “Sugar Killer” diminishes sugar in urine; Profuse miturition loaded with sugar, extreme weakness after passing large quantities of urine. Polyuria; day and night.
Helleborus (Snow-rose) 3X, 3: Frequent urging to urinate but small quantities emitted, profuse urination, urine pale and watery, dropsical swelling.
Helonias-Chamailirium (Uricorn-root) ?, 6: DM and insipidus, urine profuse and clear, phosphatic and albuminous, great thirst, restlessness, profound melancholy, irritable, boring pain across the lumbar region.
Insulin 3X, 6X: Supposed to be specific and useful in case of carbuncles resulting from DM.
Lacticum acidum (Lactic acid) 6, 30: Frequent passing of large quantities of sugar in urine, great thirst, rheumatic pains in joints.
Natrum Phosphoricum 6X, 12X and Natrum Sulphuricum 3X, 12X, 30: They are of great value in diabetes. Profuse urination, urine loaded with bile, lithic deposition in urine, sedentary habits especially when there is a succession of boils.
Phosphoricum acidum (Phosphoric acid) 2X, 30: Frequent and profuse watery urination, milk-like urine, great debility.
Phosphorus 3, 30: DM in phthisis in impotency, urine contain large amount of salt in the morning and excess of sugar in the evening.
Plumbum metallicum (Lead) 6, 30: Urine frequent, scanty, albuminous, low specific gravity.
Rhus aromatica (Fragrant sumach) ?: Large quantity of urine, urine pale, albuminous, specific gravity low.
Syzygium Jambolanum (Jambol seeds) ?: It has a specific action in diminishing and causing to disappear the sugar in urine, great thirst, and weakness, urine in very large quantities, specific gravity high. Ten drops to be taken twice or thrice daily.
Uranium nitricum (Nitrate of Uranium) 3X, 30: Profuse urination, debility, acid in urine, incontinence, unable to retain urine, excessive thirst, diarrhea of the dyspepticus.
Terebinthinum (Turpentine) 3, 6: Profuse, cloudy, smoky, and albuminous urine, sediments like coffee grounds, haematuria.
Other valuable medicines are: Arsenicum iodatum; Aurum metallicum; Boricum acidum; Bryonia alba; Chamomilla umbellate; Chionanthus virginica; Coca (Erythroxylon coca); Crotalus horridus; Curare; Iris versicolor; Kreosotum; Morphinum; Nux vomica; Pancreatinum; Silicea terra; Strychninum arsenicosum.

CREDIT TO THE WRITER
 
  booobooo on 2010-08-09
This is just a forum. Assume posts are not from medical professionals.
Great job BoooBooo.

Pankaj Varma
 
PANKAJ VARMA 9 years ago
To BooooBoooo

Thank you for another interesting article copied by you from some source which you did not identify.

I would like to share with you and others who may read this thread my experience with using Arnica 6c in the Wet dose in the treatment of Diabetes. I discovered this unusual attribute to Arnica in 2005 when I gave the 6c in pellets to a close friend of mine who was himself a doctor. He was suffering from a non healing wound on is big toe which was causing him pain due to his Diabetes of which he was the Type I and used Insulin 3 times daily.

He phoned me the day after I gave him the Arnica and expressed complete surprise that the pellets of Arnica had brought down his Blood Sugar to a level it had not dropped ever before. Being a doctor he also informed me that he could not understand how just 3 pellets could have had such a profound effect on his Blood Sugar levels and that he was not taking any unnecessary risk in taking both Insulin and the Arnica as he felt that the Arnica could do him some harm and that he was stopping it.

I followed up this information by giving Arnica 6c in the Wet dose to some other patients and the majority of them confirmed that Arnica did in fact reduce Blood Sugar levels by up to 33% which enabled the Type I patients to reduce their intake of Insulin by this percentage. They also confirmed that in common with Type II Diabetics, they felt physically much better by reducing the drug or Insulin to maintain a BS level of around 100-110.

I had an interesting case a few months ago of a patient 47 years old who had been diagnosed as a Diabetic 2 years prior who was taking 800mg Metformin morning and 400mg at night. He was compelled to stop the Metformin as he presented a case of Contact Dermatitis caused by an allergy to the drug. He had been given an alternative but this too caused even more discomfort as he felt as if he was overheated and likened his state to exuding fire from his body.

When he consulted me his BS level was 535 and I gave him Arnica 6c in the Wet dose with strict instructions to maintain the dosage of the drug but to watch how low his BS level responded to enable him to balance it to normal levels. Contrary to my instructions this patient stopped the drug and only took the Arnica as his discomfort with the allergy was acute.

He brought his BS level report and to my surprise I found it to be 105 without the drug, using only Arnica 6c twice daily. His BS levels have been monitored for the last 3 months and he seems to have stabilized at 100 which is accepted as normal. He is now experimenting with a little sugar in his tea but reported that this did not make any difference in his BS levels.

It can safely be presumed that this patient can take Arnica 6c in the future as it alone can control his BS levels.

I am copying some links to posts made by Diabetics who have recorded their own experience with Arnica and also Cinnamon powder, Okra and Bitter Gourd juice which have all helped to reduce BS levels:

http://www.abchomeopathy.com/forum2.php/30

http://www.abchomeopathy.com/forum2.php/38428/

http://www.abchomeopathy.com/forum2.php/37658/


The Wet dose of any Homeopathic remedy is made up as follows:

Order the remedy in a 5ml Ethanol pack also known as Liquid Dilution.
Get a 500ml bottle of Spring Water from the nearest supermarket.
Pour out about 3cm of water from the bottle to leave some airspace.
Insert 3 drops of the remedy into the bottle and shake it hard to produce bubbles.
This is homeopathic succussion and must be done every time before a capful of the bottle which is the dose is sipped as directed.
 
Joe De Livera 9 years ago
Dear Joe...Thank you for your concern shown. I too am Diabetic and effecting good control due to the above.

I am here only to help and nothing else. What matters most to me is to be able to reach people who either cannot afford or are misguided by doctors.

A lot of members here are guiding with the same interest of helping people.
 
booobooo 9 years ago
To BooBoo

I was interested to learn that you are a Diabetic and that you were helped by the Arnica.

It would be of interest to me and to other members to learn precisely how Arnica has helped you. Please quote BS levels before using my therapy and after and also if you are taking any drugs to add to the action of the Arnica.

You may like to know that the 47 year old Diabetic patient whom I referred to above surprised me on his last visit when he informed me that he had deliberately NOT taken Arnica for a whole week and his BS level rose to 106 WITHOUT Arnica.

This is, I believe, an indication that the Arnica he had taken for a few months had stimulated his Pancreas to start producing Insulin on demand.

It is unfortunate that my discovery which is of great international importance to the world of Diabetics is not given the publicity that it deserves as Big Pharma will stand to lose their revenue which they derive from Diabetic patients.

I have tried to spread news of this important discovery to the News media but they have not even answered my emails.

Can you please contact me by email ?

Joe De Livera
 
Joe De Livera 9 years ago
For the record I would like to add that my patient does NOT take any other drug to keep his BS under control.
 
Joe De Livera 9 years ago
Dear Joe...My BS at the momeent hover around 140. I have been taking Arnica for the last 42 days. But, I also use Insulin 25/75 premix 30Ml. too.
 
booobooo 9 years ago
Did you notice any reduction of your BS level after taking Arnica 6c?

Many patients both Type I and Type II have reported that they noticed a drop of around 30% in their BS levels within 12 hours after their first dose taken twice daily. I instructed them to reduce the Metformin or the units of Insulin to keep their BS level around 100.

I am 81 years old and do not have any Diabetes and in fact any other illness that is normally accepted as the price of growing old.

I believe that this is due to my daily dose of Arnica 30 in the Wet dose that I have taken since 1996.
 
Joe De Livera 9 years ago
Not as yet as it is too early. I will have to stop my insulin to actually see the effect.
 
booobooo 9 years ago
You cannot and must not STOP your Insulin. Many patients have confirmed that they noticed a perceptible dip in their BS level within 6 hours of their first dose of Arnica. All they have to do at that stage is to monitor their BS level and keep it around 100 + or - 10.

If you are one of the fortunate ones you should observe in a few days that your Insulin demand should be about 30% below what you used without Arnica.

Do keep me posted of your response.
 
Joe De Livera 9 years ago
Shall keep you posted on BS levels.
 
booobooo 9 years ago
Just checking on your BS levels today.

What is your BP ?
 
Joe De Livera 8 years ago
Sorry for my absence as I was not well. Diabetes is well within the parameters of control with no BP problems.
 
booobooo 7 years ago
BB

Welcome back.

I missed you for some months.

Do contact me by email.

Joe
 
Joe De Livera 7 years ago
Hi Booboo,
Your article is highly helpful
to understand the intricacies of the disease.
I have a very interesting case of my friend's mother aged 50 yrs.Having diabetes since age of 35yrs,having 3 sons the interesting thing is that she doesn't have that typical thirst as well as frequent urination.BP normal.However her son reports that she is mentally highly irritable and keeps talking all negative mainly to her daughters in law in general she is talkative,5'8'
illiturate,Gujrati lady.
She has peripheral neuropathy prominently in left foot to calf which is charecterised by brown spots from fingers to calf level also pain below knee to foot in left leg.She also had lots of lumber/spinal pains in past which are not there now,but sleeps less in night,along with Arnica,presntly I am thinking about Helonius which she is prresnting mentals and generals the only thing she doesn't have profuse urination of Helon.
This is very peculier case as she doesn't have those symptoms of Diabetes,Oh yes her latest BS is 330(fasting)and 370(pp).
 
bapu4 5 years ago
You could look at Lachesis. Her mentals look like she is one...besides, she is menopausal and doesn't sleep well.
 
rishimba 5 years ago
OK Thanks a lot rishimba
 
bapu4 5 years ago

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Important
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